Detalhe da pesquisa
1.
High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.
Annu Rev Pharmacol Toxicol
; 64: 191-209, 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37506331
2.
XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA.
Genes Cells
; 27(5): 331-344, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35194903
3.
Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation.
Arch Toxicol
; 96(7): 1975-1987, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35435491
4.
Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites.
Proc Natl Acad Sci U S A
; 115(33): 8412-8417, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061412
5.
Application of In Vitro Metabolism Activation in High-Throughput Screening.
Int J Mol Sci
; 21(21)2020 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33142951
6.
Liver three-dimensional cellular models for high-throughput chemical testing.
Cell Rep Methods
; 3(3): 100432, 2023 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37056374
7.
Lestaurtinib induces DNA damage that is related to estrogen receptor activation.
Curr Res Toxicol
; 4: 100102, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36619290
8.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
bioRxiv
; 2022 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665018
9.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Sci Adv
; 8(48): eadd4150, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36449624
10.
Pold4, the fourth subunit of replicative polymerase δ, suppresses gene conversion in the immunoglobulin-variable gene in avian DT40 cells.
DNA Repair (Amst)
; 100: 103056, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33588156
11.
Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition.
Environ Health Perspect
; 129(4): 47008, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33844597
12.
Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential.
Front Bioeng Biotechnol
; 8: 109, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32154236
13.
PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching.
PLoS One
; 14(3): e0213383, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30840704
14.
Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression.
PLoS One
; 13(2): e0192421, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29408941
15.
SPARTAN promotes genetic diversification of the immunoglobulin-variable gene locus in avian DT40 cells.
DNA Repair (Amst)
; 68: 50-57, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29935364
16.
The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C).
Oncotarget
; 8(20): 33457-33474, 2017 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28380422
17.
ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.
PLoS One
; 12(11): e0188320, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149203
18.
Cytotoxic and genotoxic profiles of benzo[a]pyrene and N-nitrosodimethylamine demonstrated using DNA repair deficient DT40 cells with metabolic activation.
Chemosphere
; 144: 1901-7, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26547024
19.
Determination of genotoxic potential by comparison of structurally related azo dyes using DNA repair-deficient DT40 mutant panels.
Chemosphere
; 164: 106-112, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27580264
20.
Development of a targeted flip-in system in avian DT40 cells.
PLoS One
; 10(3): e0122006, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25799417